With its meticulously executed craft cocktails and thoughtfully curated natural wine list, Cicatriz has changed the game for drinking in Juarez. Owned by New York transplants and siblings Scarlett and Jake Lindeman, the relaxed drinks destination combines new American style dishes, like an indulgent crispy chicken sandwich, with signature drinks like the Yokos, the house version of an Aperol spritz. [Disclosure: Scarlett Lindeman has contributed to Eater as a writer, Jake Lindeman as a photogropaher.]

As you enter this hidden bar, the bohemian smell of copal incense welcomes you to a night of mellow music and fancy cocktails. Xaman’s list plays with local ingredients like guava and hoja santa, which find their way into fermented syrups, bitters, and other boozy concoctions. Local and foreign artists blend in alongside an edgy business crowd, so be prepared to people-watch with cocktail in hand.

Set in the financial district of the Cuauhtémoc borough, this contemporary haunt is dominated by an old cantina-style bar that doles out beer, mezcal, and a mix of cocktails. Patrons belly up for leisurely dominos sessions set to a soundtrack of ranchero and Mexican folk classics. At the tables, a mixed crowd digs into hearty portions of Mexican cantina recipes, like chamorro or spicy shrimp. On Thursday nights, climb the stairs to the hidden tropical dance hall, Babalú, with salsa and bachata set to live music.

This wine bar hidden down a little nook off Roma Norte is the frontrunner in D.F.’s burgeoning natural wine scene. Chef Joaquin Cardoso (best known for his work at the Hotel Carlota) and wine director Gaëtan Rousset teamed up to offer an amazing selection of organic, biodynamic wines — mostly French and Mexican — and a delicious menu to pair them with.

Located on a busy corner in Roma, Can Can bar draws inspiration from cocktail classics like the Long Island iced tea (vodka, gin, tequila, rum, black tea, and lime) and the Moradito (vodka and grape juice), but those in the know go for the Moscow mule. The bartenders (also behind the award-winning bar Limantour) give the retro libations a high-end twist. The throwback drinks match the not-too-serious spirit, but the bartenders here know what they’re doing.

This industrial temple to all things hops offers a delicious glimpse of the Mexican craft-beer scene, with 22 taps dedicated to small local producers. If not everyone’s up for a brew, there is also plenty to quench the thirst of cocktail and mezcal lovers. The relaxed vibe here makes it a popular weeknight stop.